To commemorate the 40th anniversary of the Council for the United States and Italy, we organized a Dinner Round Table at the Luiss University Campus in Rome. To celebrate such an important milestone, throughout the evening we addressed several topics including the impact of artificial intelligence on three key sectors, education, security and defense, and culture. We deeply thank Minister Anna Maria Bernini (Minister for University and Research), Roberto Cingolani (CEO, Leonardo), and Evelina Christillin (President, Egyptian Museum Foundation) for their insightful contributions.